Special Lectures

Thursday June 10, 2004Gthe first day

GranShip•Medium Hall•Earthi1,2,3 Fj

Special Lecture I
11:20|12:00

Isogenies of drugs and food, and metals
Yoshinori ITOKAWA
iProfessor Emeritus, Kyoto University•Medicinej
ChairpersonFYasuaki ARAKAWA (Professor, The university of Shizuoka)

Special Lecture II
13:50|14.30

Essentiality and Toxicity of Metals -Fundamental and Practical considerations-
Osamu WADA
iProfessor Emeritus, The University of Tokyo•Medicinej
ChairpersonFHiromu SAKURAI (Professor, Kyoto Pharmaceutical University)

Friday June 11, 2004Gthe second day

GranShip•Medium Hall•Earthi1,2,3 Fj

Special Lecture III
14.40|15:20

Elucidation and Application of Intrinsic Properties of Molecular Recognition by Zinc Ions in Biology
Eiichi KIMURA
iex-President, The Pharmaceutical Society of Japanj
ChairpersonFTetsuo NAGANO (Professor, The University of Tokyo)

Topic Lecture

Thursday June 10, 2004Gthe first day

GranShip•Medium Hall•Earthi1,2,3 Fj

Topic Lecture
13:10|13:50

Isogenies of drugs and food, and metals
Atsuko ADACHI
iHead, Hyogo Prefectural Kakogawa Hospital, Devmatologyj
ChairpersonFHiroyuki YANAGISAWA (Professor, Saitama Medical University)

Lectures

Thursday June 10, 2004GFirst day

GranShip•Medium Hall•Earthi1,2,3 Fj

Session I@Development of New Metal Drugi9:20|10:20j

Chairperson : Hideo SAJI (University of Kyoto)
Lecture 1
A 99mTc-labeled hydrazino nicotinamide derivatized bisphosphonate for bone scintigraphy
›Kazuma OGAWA1,2, Takahiro MUKAI1,3, Yasuyuki INOUE1, Hideo SAJI1
1)Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan 2)Central Institute of Radioisotopes Science, Division of Tracer Kinetics, Advanced Science Research Center, Kanazawa University, Kanazawa, Japan 3)Department of Biomolecular Recognition Chemistry, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
Lecture 2
A new potent insulin-mimetic vanadyl(IV)-allixin complex
›Yusuke ADACHI1, Jiro YOSHIDA2, Yukihiro KODERA2, Akira KATOH3, Hiromu SAKURAI1
1)Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan 2)Healthcare Institute, Wakunaga Pharmaceutical Co., Ltd., Hiroshima, Japan 3)Department of Applied Chemistry, Faculty of Engineering, Seikei University, Tokyo, Japan
Lecture 3
Non-covalent interactions of an antitumor dinuclear platinum(II) complex with DNA
›Wada RYUHEI1, Sachie WADA1, Takaji SATO1, Katsuhiko MINOURA1, Keiko NOGUCHI1, Keiko FUJII1, Seiji KOMEDA1, Yoshihiro SAITO1, Masahiko CHIKUMA1
1)Osaka University of Pharmaceutical Sciences

Session II@Design of Functional Metal Moleculei10:20|11:20j

Chairperson : Osamu YAMAUCHI iKansai Universityj
Lecture 4
Structure-based design of the irreversible inhibitors to metallo-β-lactamase (IMP-1)
›Yoshihiro YAMAGUCHI1, Kimitaka SOGA1, Toshihiro HIGASHI1, Shogo MISUMI2, Hiromasa KUROSAKI1, Yuriko YAMAGATA3, Yoshichika ARAKAWA4, Masafumi GOTO1
1)Department of Structure-Function Physical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University 2)Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University 3)Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kumamoto University 4)Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases
Lecture 5
Co(III) complexes of an N2S3-type ligand designed as an active site model of nitrile hydratase: Influences of the oxygenated sulfurs on the central metal ion
›Tomohiro OZAWA1, Tomohiro IKEDA1, Yasuhiro FUNAHASHI1, Koichiro JITSUKAWA1, Hideki MASUDA1
1)Graduate School of Engineering, Materials Science & Engineering, Nagoya Institute of Technology, Nagoya, Japan
Lecture 6
Syntheses and Functional Analyses of Artificial Zinc Finger Proteins Linked with Metal Complex Moiety
›Akira ONDOA1, Nozomi ARAI1, Shigenori KOBAYASHI1, Kenji KANEKO1, Takeshi YAMAMURA1
1)Department of Chemistry, Faculty of Science, Tokyo University of Science, Tokyo, Japan

Session III@Biological Activity of Organometal in an Ecosystem \ Marine Lifei14:40|15:20j

Chairperson : Hiroyuki NAKAZAWAiHoshi Universityj
Lecture 7
Effect of tributyltin on reproduction of fish and shellfish
›Yuji OSHIMA1, Shimasaki YOHEI1, Suguru INOUE2, Kei NAKAYAMA2, Tsuneo HONJO1
1)Faculty of Agriculture, Kyushu University, Fukuoka, Japan 2)Center for Marine Environmental Studies, Ehime University, Ehime, Japan
Lecture 8
Imposex induced by organotin compounds in gastropods: from molecular mechanism to population-level effects
›Toshihiro HORIGUCHI1, Hiroaki SHIRAISHI1, CHO HYEON-SEO2, Yasuhiko OHTA3, Taisen IGUCHI4, Tomohiro NISHIKAWA1, Fujio SHIRAISHI1, Masatoshi MORITA1, Jun-ichi NISHIKAWA5
1)Endocrine Disruptors & Dioxin Research Project, National Institute for Environmental Studies, Tsukuba, Japan 2)Yosu National University, Yosu, Korea 3)Faculty of Agriculture, Tottori University, Tottori, Japan 4)Center for Integrative Bioscience, Okazaki National Research Institutes, Okazaki, Japan 5)Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

Session IV Biological Activity of Organometal in an Ecosystem \ Land Lifei15:20|16:20j

Chairperson : Seiichiro HIMENO (Tokushima Bunri University)
Lecture 9
Triphenyltin (TPT) chloride increased production of interleukin-1β (IL-1β) by murine macrophages after subacute oral exposure
›Masashi TSUNODA1, Ken NAKANO2, Nobuhiro KONNO3
1)Department of Public Health, Fukushima Medical University, Fukushima, Japan 2)Fukushima Institute of Public Health, Fukushima, Japan 3)Koriyama Women's University & College, Koriyama, Japan
Lecture 10
Metabolism of triphenyltin
›Shuji OHHIRA1, Mitsunori ENOMOTO1, Yoshikazu MIURA1, Hisao MATSUI1
1)Department of Hygiene, Dokkyo University School of Medicine, Tochigi, Japan
Lecture 11
Effects of organoltin compounds on endocrine functions of human placental cells
›Tsuyoshi NAKANISHI1, Jun-ichi NISHIKAWA2, Keiichi TANAKA1
1)Department of Toxicology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan 2)Laboratory of Environmental Biochemistry, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

Session V@Development of New Metal-Complex•Metal-Probei16:20|17:20j

Chairperson : Saburo NEYA (Chiba Universityj
Lecture 12
Radiometal Labeled Probes for in vivo Redox Imaging
›Takako FURUKAWA1, Takeshi TANAKA2, Yasuhisa FUJIBAYASHI1
1)Biomedical Imaging Research Center, University of Fukui, Fukui, Japan 2)Department of Otorhinolaryngology
Lecture 13
Design and Synthesis of a Novel Lanthanide-based Zinc Ions-Sensitive Chemosensors for Magnetic Resonance Imaging (MRI) and/or Luminescence Measurement
›Kenjiro HANAOKA1, Kazuya KIKUCHI1,2, Tetsuo NAGANO1
1)Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan 2)Presto, JST Corporation, Kawaguchi, Saitama, Japan
Lecture 14
A Versatile Strategy for the Synthesis of Crown Ether Bearing Heterocycles: Discovery of Calcium Selective Fluorescent Probe
Yuko AOKI1, Naoki UMEZAWA1, Yuko ASANO1, Kei-ichiro HATANO1, Shin-ichi NAGAI1, ›Tsunehiko HIGUCHI1
1)Graduate School of Pharmaceutical Sciences, Nagoya City University

Friday June 11, 2004GSecond day

GranShip•Medium Hall•Earthi1,2,3 Fj

Session VI@Metal and Biological Function|1i9:00|9.40j

Chairperson : Masayoshi YAMAGUCHI (University of Shizuokaj Lecture 15
Immune disrupting effect of arsenic; Inorganic arsenite induces HLA-DR strong positive dendritic macrophage generation from human peripheral blood monocytes
›Teruaki SAKURAI1, Takami OHTA1, Kitao FUJIWARA1
1)Laboratory of Environmental Chemistry, School of Life Science, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
Lecture 16
Molecular mechanism of cytolethality of dimethylated trivalent arsenic compound
›Chikara KOJIMA1, Teruaki SAKURAI1, Kitao FUJIWARA1
1)Laboratory of Environmental Chemistry, School of Life Science, Tokyo University of Pharmacy and Life Science, Tokyo, Japan

Session VII@Metal and Biological Function|2i9.40|10.40j

Chairperson : Masahiro KAWAHARA (Kyushu University of Health and Welfarej
Lecture 17
Role of zinc in the regulation of protein tyrosine phosphatase activity in osteoblastic MC3T3-E1 cells
Masayo FUKAGAWA1, ›Satoshi UCHIYAMA1, Masayoshi YAMAGUCHI1
1)Graduate School of Nutritional Sciences, University of Shizuoka
Lecture 18
Inhibitory zinc action against excitation of hippocampal glutamatergic neurons
›Akira MINAMI1, Atsushi TAKEDA1, Jun-ichi KOSUGE2, Noboru FUKASAKU2, Tetsuo NAGANO3, Naoto OKU1
1)Department of Medical Biochemistry, School of Phrmaceutical Sciences, University of Shizuoka, Shizuoka, Japan 2)Daiichi Pure Chemicals Co., LTD., Ibaraki, Japan 3)Laboratory of Bioorganic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Lecture 19
Studies on the valid utilization of abundant zinc contained in Oyster (Crassostrea gigas)
›Yoshikazu MATSUDA1, Natsumi SUMIDA2, Sachiko KITANI2, Shoko KITANI2, Mamiko ABE1, Nami KOMURA1, Tomoe KAWASHIMA1, Kenji FUKUNAGA2, Munehiro YOSHIDA2
1)Central Research Institute, Japan Clinic Co., Ltd., Kyoto, Japan 2)Department of Biotechnology, Faculty of Engineering, Kansai University, Osaka, Japan

Session VIII@Metal and Biological Function|3i10.40|11.20j

Chairperson : Atsushi TAKEDA (University of Shizuokaj
Lecture 20
Activation of Iron Regulatory Protein 1 through Heme Oxygenase 1 Signaling Pathway after Oxidative Stressful Stimuli
›Satoru OSHIRO1, Koji NOZAWA2, CHUN ZHANG3, Toshio SONE4, Ken-ichi KAWAMURA5
1)Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan 2)Showa College of Pharmaceutical Sciences, Tokyo, JAPAN 3)Van Andel Research Institute, Michigan, USA 4)Allergy and Immunology, Saitama Medical School, Saitama, JAPAN. 5)TK Craft Co., LTD, Gunma, Japan
Lecture 21
Implications of calcium homeostasis and neurotrophic factors in neurotoxicity of aluminum on primary cultured neurons
Keiko KONOHA1, Yutaka SADAKANE1, Lisa IMAMURA2, Masaaki TSUDA2, ›Masahiro KAWAHARA1
1)Department of Analytical Chemistry, School of Pharmaceutical Sciences, Kyushu University of Health and Welfare, Miyazaki, Japan 2)Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Toyama, Japan

Session IX@Analytical Method of Metalsi11:20|12:00j

Chairperson : Shuichi Enomoto (RIKENj
Lecture 22
A robust speciation method for arsenic in biological matrices by ion-exclusion chromatography-ICPMS using reaction cell and hydride generation techniques
›Tetsuya NAKAZATO1, Hiroaki TAO1
1)Institute for Environmental Management Technology, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
Lecture 23
Analysis of inorganic antimicrobial agents used in antimicrobial products
›Harunobu NAKASHIMA1, Ooshima TOMOKO2
1)Osaka Prefectural Institute of Public Health, Osaka, Japan 2)Osaka City Institute of Public Health and Environmental Sciences, Osaka, Japan

Session X@Metal-Associated Bio-Chemical Reaction|1 i15.20|16.00j

Chairperson : Toshihiko OZAWA (National Institute of Radiological Sciencesj
Lecture 24
Reaction Intermediates Detected during the Four-Electron Reduction Process of Dioxygen by Bilirubin Oxidase Mutants
›Rieko KITAGAWA1, Megumi INOUE1, Kunishige KATAOKA1, Takeshi SAKURAI1, Yamagutchi SHOTARO2
1)Faculty of Science, Kanazawa University, Kanazawa, Japan 2)Amano Enzyme, Kamigahara, Japan
Lecture 25
Reduction of Cytchrome c with Tyrosyltyrosylphenylalanine
›Shun HIROTA1, Hisano OKUMURA2, Noriaki FUNASAKI1, Yoshihito WATANABE2
1)Department of Physical Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan 2)Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya, Japan

Session XI@Metal-Associated Bio-Chemical Reaction|2 i16:00|16:40j

Chairperson : Hideki MASUDA (Nagoya Engineering Universityj
Lecture 26
Relationship between the formation of singlet oxygen and substrate oxygenation in ethanol-induced rat liver microsomes
›Seiko HAYASHI1, Hiroyuki YASUI1, Hiromu SAKURAI1
1)The Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan
Lecture 27
Transesterification and cycle reaction using polynuclear zinc-peptide dendrimer
›Kazuhiko ICHIKAWA1, TARUNAI MATE1
1)Graduate School Of Environmental Earth Science, Hokkaidou University, Sapporo, Japan

Session XII@Structure and Property of Metal-Complex (16:40|17:20j

Chairperson : Masahiko CHIKUMA (Osaka University of Pharmaceutical Sciencesj
Lecture 28
Optical Properties of Zinc Complex of Chlorophyll-a and Its Application for Photoinduced Hydrogen Production
›Yumi TAKEUCHI1, Yutaka AMAO1
1)Department of Applied Chemistry, Oita University, Oita, Japan
Lecture 29
Structural Basis of Human Cytoglobin for Ligand Binding
›Masatomo MAKINO1,2, Hiroshi SUGIMOTO1, Hitomi SAWAI1,2, Norifumi KAWADA3, Katsutoshi YOSHIZATO4, Yoshitsugu SHIRO1
1)Biometal Science Laboratory, Riken Harima Institute, Hyogo, Japan 2)Department of Life Science, Graduate School of Science, Himeji Institute of Technology, Hyogo,Japan 3)Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, japan 4)Department of Biological Science, Graduate School of Science, Hiroshima University, Hiroshima, Japan

Poster Sessions

Friday June 11, 2004GSecond dayi13:00|14.40j

GranShip•Exhibition@Galleryi6Fj

SessionI@Development of New Metal Drug

Poster 1
Evaluation of Zn-DTS complexes as oral antidiabetic agents
›Jun ABE1, Yasuhiko IIDA2, Yasushi KIYONO3, Youji KITAMURA4, Hideo SAJI5
1)Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan 2)Faculty of Medicine, Gunma University, Maebashi, Japan 3)Kyoto University Hospital, Kyoto, Japan 4)Faculty of Pharmaceutical Sciences, Kobegakuin University, Kobe, Japan 5)Graduate School of Pharmaceutical Science, Kyoto University, Kyoto, Japan
Poster 2
Development of inhibitors of metallo-β-lactamase (IMP-1 and VIM-2)
›JIN WANCHUN1, Yoshichika ARAKAWA2, Yosihiro YAMAGUCHI1, Hiromasa KUROSAKI1, Yuriko YAMAGATA3, Michio OHTA4, Masafumi GOTO1
1)Department of Structure-Function Physical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University 2)Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases 3)Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kumamoto University 4)Department of Molecular Bacteriology, Nagoya University Graduate School of Medicine
Poster 3
Biological effects of novel binuclear platinum (II) complexes in human ovarian tumor cell lines
›Noriko AOKI1, Takaji SATO1, Maiko KODA1, Aiko SAKIYAMA1, Rei KOMAKI1, Seiji KOMEDA1, Yoshihiro SAITO1, Masahiko CHIKUMA1
1)Osaka University of Pharmaceutical Sciences, Osaka, Japan
Poster 4
Interactions of Biomolecules with Platinum(II)-Polypyridine Complexes Containing an Amino Acid. Adduct Formation and Its Effect
›Minoru TASHIRO1, Tatsuo YAJIMA1, Takeshi MOTOYAMA1, Akira ODANI2, Yasuo NAKABAYASHI1, Osamu YAMAUCHI1
1)Unit of Chemistry, Faculty of Engineering, Kansai University, Osaka, Japan 2)Reserch Center for Materials Science, Nagoya University, Nagoya, Japan

SessionII@Design of Functional Metal Molecule

Poster 5
DNA binding selectivity of artificial 6-zinc finger proteins
›Miki IMANISHI1, YAN WEI1, Yukio SUGIURA1
1)Institute for Chemical Research, Kyoto University, Kyoto, Japan
Poster 6
Interactions of glucose oxidase with dipolar ruthenium ammine complexes as electron transfer mediators of glucose oxidation
›Yasuo NAKABAYASHI1, Yuri HIROSAKI1, Masahiro KINOSHITA1, Osamu YAMAUCHI1
1)Unit of Chemistry, Faculty of Engineering, Kansai University, Osaka, Japan
Poster 7
Hetero metal-assemblage in artificial DNA
›Yusuke TAKEZAWA1, Kentaro TANAKA1,2, Tatsuhisa KATO3, Mitsuhiko SHIONOYA1
1)Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan 2)PRESTO, Japan Science and Technology Corporation (JST), Tokyo, Japan 3)Institute for Molecular Science, Okazaki, Japan
Poster 8
Syntheses of cyclometalated ruthenium(‡U) complexes and application for electron transfer mediators
›Masahiro KINOSHITA1, Yasuo NAKABAYASHI1, Osamu YAMAUCHI1
1)Unit of Chemistry, Faculty of Engineering, Kansai University, Osaka, Japan

SessionIII@Ecosystem@and@Metals

Poster 9
Effects of metals on post-embryonic development and reproduction in C. elegans
Koji ARIZONO1,4, ›Yukari KOGA1,4, Fumiyo MORITA1, Takashi NAKAMOTO1, Hirokazu KIMURA1, Kazuhiro URA2, Taisen IGUCHI3,4
1)Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, Kumamoto, Japan 2)Graduate School of Fisheries Sciences & Faculty of Fisheries, Hokkaido University, Hokkaido, Japan 3)Center for Integrative Bioscience, Okazaki National Research Institutes, Aichi, Japan 4)Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Saitama, Japan
Poster 10
Research on purification of soil and water pollution by the heavy metals using Lotus japonicus
›Rieko HIRUNUMA1, Kaori IGARASHI1, Hiroyuki SAITO1, Yutaka MIYAZAWA1, Hiromitsu HABA1, Hiroshige TAKEICHI1, Tomoko ABE1, Shuichi ENOMOTO1
1)RIKEN 2)Graduate School of Life Sciences, Tohoku University, Miyagi, Japan

SessionIV@Development of New Metal-Complex•Metal-Probe

Poster 11
Design and Synthesis of Zinc Selective Chelators
›Eri KAWABATA1, Kazuya KIKUCHI1,2, Akira ODANI3, Tetsuo NAGANO1
1)Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan 2)Presto, JST Corporation, Kawaguchi, Saitama, Japan 3)Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya, Aichi, Japan

SessionV@Metal and Biological Function

Poster 12
Susceptibility to excitotoxity of glutamate under zinc deficiency and effect of saiko-ka-ryukotsu-borei-to, a herbal medicine, on the excitotoxity
›Haruna TAMANO1, Atsushi TAKEDA1, Naoto OKU1
1)Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
Poster 13
Bioavailability of zinc yeast in rats: Stimulatory effect on bone calcification in vivo
›Satoshi UCHIYAMA1, Aki IGARASHI1, Masayoshi YAMAGUCHI1
1)Graduate School of Nutritional Sciences, University of Shizuoka
Poster 14
The role of glutathione in the stability of biliary arsenic metabolites, arsenic triglutathione [As(GS)3] and methylarsenic diglutathione [CH3As(GS)2]
›Yayoi KOBAYASHI1,2, Seishiro HIRANO1
1)Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan 2)Japan Foundation for Aging and Health, Chita, Aishi, Japan
Poster 15
Distributions of 67Cu in hepatoma rats and Cu chaperone knock-down HepG2 cells
›Akihiro NAKAYAMA1, Hiromitsu HABA1, Shuichi ENOMOTO1
1)Cyclotron Center, RIKEN, Saitama, Japan

SessionVI@Metal@Analysis

Poster 16
Elution behavior of elements from insoluble minerals as food additives in the manufacturing process of liquid food
›Takashi AMAGASA1, Rie ITO1, Koichi INOUE1, Yoshihiro YOSHIMURA1, Makiko YAMADA2, Teruhisa FUJIMAKI3, Masakazu HORIE4, Hiroyuki NAKAZAWA1
1)Faculty of Pharmaceutical Science, Hoshi University 2)SaneigenFFI, Tokyo, Japan 3)Kanagawa Institute of Health, Kanagawa, Japan 4)Saitama Institute of Health, Saitama, Japan
Poster 17
NMR analysis of mouse urine: application to toxicity evaluation of trace elements
›Hideki MIYATAKA1, Toshiyuki OZAKI1, Seiichiro HIMENO1
1)Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan

SessionVII@Metal-Associated Bio-Chemical Reaction

Poster 18
Radical-Scavenging Reactions of 4-Hydroxycinnamic Acid Derivatives in the Presence of Metal Ions
Ikuo NAKANISHI1,2, Yoshihiro UTO3, ›Tomonori KAWASHIMA1,4, Haruko YAKUMARU1, Hideko KANAZAWA4, Toshihiko OZAWA1, Hideko NAGASAWA3, Hitoshi HORI3, Nobuo IKOTA1
1)Redox Regulation Research Group, National Institute of Radiological Sciences, Chiba, Japan 2)Department of Material and Life Science, Graduate School of Engineering, Osaka University, CREST, Japan Science and Technology Agency, Osaka, Japan 3)Department of Biological Science & Technology, Faculty of Engineering,The University of Tokushima, Tokushima, Japan 4)Department of Physical Chemistry, Kyoritsu College of Pharmacy, Tokyo, Japan
Poster 19
Effects of Metal Ions on the Stability of Oxygen and Nitrogen Radicals
›Ikuo NAKANISHI1,2, Tomonori KAWASHIMA1,3, Hideko KANAZAWA3, Kei OHKUBO2, Kiyoshi FUKUHARA4, Toshihiko OZAWA1, Shunichi FUKUZUMI2, Nobuo IKOTA1
1)Redox Regulation Research Group, National Institute of Radiological Sciences, Chiba, Japan 2)Department of Material and Life Science, Graduate School of Engineering, Osaka University, CREST, Japan Science and Technology Agency 3)Department of Physical Chemistry, Kyoritsu College of Pharmacy 4)Division of Organic Chemistry, National Institute of Health Sciences

SessionVIII@Structure and Property of Metal-Complex

Poster 20
Control of geometric stability and spin state of the iron(III) atom by isomeric porphyrins
›Saburo NEYA1, Tyuji HOSHINO1, Masayuki HATA1
1)Department of Physical Chemistry, Graduate School of Phramaceutical Sciences, Chiba University
Poster 21
Increased binding affinity of aluminum in the presence of oxalate for asialo-transferrin compared with native-transferrin studied by HPLC/HR-ICP-MS
›Megumi HAMANO NAGAOKA1, Hiroshi AKIYAMA1, Tamio MAITANI1
1)Division of Foods, National Institute of Health Sciences
Poster 22
The Metal Binding Motif of Dipeptidyl Peptidase III Directly Influences the Enzyme Activity in the Copper Derivative of Dipeptidyl Peptidase III
›Junzo HIROSE1, Hiroshi KAMIGAKIUTI1, Hiroyuki IWAMOTO1, Satoru YAMAMOTO2, Kayoko FUKASAWA3
1)Department of Applied Biological Science, Fukuyama University, Fukuyama, Japan 2)Department of Biotechnology, Fukuyama University 3)Department of Oral Biochemistry, School of Dentistry, Matsumoto Dental University
Poster 23
Roles of Heme Axial Ligands in the Regulation of CO Binding to CooA
›Taku YAMASHITA1, Youhei HOASHI1, Kimiko WATANABE1, Yoshikazu TOMISUGI1, Yoshinobu ISHIKAWA1, Tadayuki UNO1
1)The Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Poster 24
Study on Structures and Characterizations of Linear Au(I) Thiolato Complexes
›Yuki MATSUNAGA1, AMIR NAGINA1, Yoshitaro MIYASHITA1, Kiyoshi FUJISAWA1, Ken-ichi OKAMOTO1
1)Department of Chemistry, University of Tsukuba, Ibaraki, Japan
Poster 25
Syntheses of dinuclear ruthenium(II)-2,2'-bipyridine complexes and characterization of their DNA-binding activities
›Nobuaki IWAMOTO1, Yasuo NAKABAYASHI1, Osamu YAMAUCHI1
1)Faculty of Engineering, Kansai University, Osaka, Japan